It didn’t take much for Jerry to lose interest in his different partners throughout the show, mostly for the most random reasons. Take Donna for example — all it took to end things between them was for her to like a commercial he hates in “The Phone Message”. Sounds pathetic? Welcome to Jerry’s relationships.
Playing Donna is actress Gretchen German, and while her appearance on Seinfeld was pretty short, she went on to have small roles in shows like “Will & Grace” and “Criminal Minds”. She is currently working on a TV movie called “Bad Therapist”. Sounds promising!
Isabel
Actress Tawny Kitaen is another one of the women who got cast as one of Jerry's girlfriends despite being WAY out of his league. The episode in question is titled "The Nose Job" and was aired in 1991. Isabel's good looks on one hand and her unbearable personality on the other spark an epic game of chess between Jerry's brain and his... let's call it "reproductive parts". (The brain wins.)
Since her Seinfeld stint, Kitaen was featured in different shows such as "Hercules: The Legendary Journeys" and "The New WKRP" in the 90s but hasn't participated in many acting projects since. Actually, lots of her on-screen appearances in the 2000s were as herself in reality TV shows such as "Botched".
Laura
Men having a hard time figuring out women's signals are nothing new, and Jerry can tell you all about it. When he is contacted by Laura (Pamela Brull), who is asking to stay with him during her visit to New York. Some might think she has romantic intentions, Jerry sure thought so, only to find out she was actually engaged and simply being friendly. Oh, the awkward factor... And to think it was in the first episode!
Actress Pamela Brull played Laura way back in 1989. She later kept getting small acting parts, mostly in TV shows and TV movies. That being said, her latest acting credit is from 1997 and she appears to have retired since.
Angela
In "The Good Samaritan", Jerry tries to do the right thing for a change and confront a driver who committed a hit and run. The thing is, the driver turns out to be a beautiful woman named Angela and Jerry ends up asking her out instead.
Angela is played by Melinda McGraw, who went on to have various roles, mostly on TV. She has even appeared in "Mad Men", "The West Wing", and "NCIS". Her most recent on-screen appearance was as a recurring role in the TV remake of the series "Charmed".
Gail
Actress Anita Barone plays Gail Cunningham, a woman who has dated Jerry three times, all the while refusing to touch him. Normally, there would be nothing wrong with that, only she kissed Kramer after he walked her home one time in the episode "The Shoes".
Not many people know this, but Anita was the original casting choice for Carol, Ross's lesbian wife on "Friends", but only did it in one episode. Don't worry about her, though, she got other recurring roles in other TV shows — most recently as Sabrina in "Brew Brothers".