A Chinese Shar-Pei, Fu Dog is a magical animal guardian to Jake Long and Jake’s grandfather Lao Shi. He assists with training Jake and provides lots of information about magical creatures and items.
Fu is able to walk upright thanks to his magical nature but has no trouble masquerading as a “normal” dog. He is stated to be over six hundred years old and has been feuding with a similarly magical cat named Yan Yan for some time, all over a lucky coin. Fu Dog is based on a Chinese architectural ornament called a Foo Dog which, among a number of things, is said to offer protection from spirits.
Rufus from “Kim Possible”
He isn't a cat or a dog, but if anybody tries to separate Rufus from his loving owner Ron Stoppable, there's going to be trouble. This cute little naked mole-rat doesn't even have any fur, but he still loves Tex-Mex, adventures, and Kim, just like Ron does.
It's hard to count the number of times Rufus has gotten Kim or Ron out of sticky situations, or the number of times that Rufus has bombed Ron's schemes to be more popular or cooler in school. He's voiced by Nancy Cartwright, who is best known for her long-running role as Bart Simpson.
Astro Jetson from “The Jetsons”
As the space-age mirror to the stone-age Flintstones, the Jetsons presented their own take on modern life, showing us the far-flung future. Astro is the family dog that first appeared with the family in 1962.
Even though he causes plenty of stress to owner George Jetson, Astro is a best friend to the family. Though clumsy and dim-witted, he's loyal to everyone in the family. The dog can talk in rough “dog-sounding” English thanks to Don Messick. If you've ever thought that Scooby and Astro sound similar, that's because they share Messick and basically have the same voice.
Azrael from “The Smurfs”
Even if you only know about the animated cartoon show that began in the eighties, Azrael and his master Gargamel have been trying to catch and eat the blue-skinned Smurfs since 1959.
The characters originally began in a comic by Pierre Peo Culliford, a Belgian cartoonist. Azrael, an orange tabby, loves spending time with the evil wizard Gargamel, even if the wizard does end up blaming the cat for all of his failures. Despite this, he remains loyal to his owner, even if he does like to snicker at Gargamel's failed schemes. Azrael's name comes from an Angel of Death, which is quite terrifying, and great for an evil wizard's pet.
Perry the Platypus from “Phineas and Ferb”
Most of the animals on this list are cats or dogs, but Perry will be the only platypus seen. Even though Phineas and Ferb say that he doesn't do much, it turns out Perry has a secret life – that of a secret agent of O.W.A., who constantly battles against the scientist Heinz Doofenshmirtz.
Doofenshmirtz's dangerous -inators constantly threatened the tri-state area, but Perry was always there to stop him. Nobody in the family knows about Perry's double life, and it has to stay that way, or the family's memories will be wiped and Perry will have to be relocated. Perry loves the brothers, and even Candice, their sister, and doesn't want that to happen.